Best Linear Unbiased Allele-Frequency Estimation in Complex Pedigrees
نویسندگان
چکیده
منابع مشابه
Best linear unbiased allele-frequency estimation in complex pedigrees.
Many types of genetic analyses depend on estimates of allele frequencies. We consider the problem of allele-frequency estimation based on data from related individuals. The motivation for this work is data collected on the Hutterites, an isolated founder population, so we focus particularly on the case in which the relationships among the sampled individuals are specified by a large, complex pe...
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ژورنال
عنوان ژورنال: Biometrics
سال: 2004
ISSN: 0006-341X
DOI: 10.1111/j.0006-341x.2004.00180.x